Five-star
The five-star edit
9.601Sofitel Legend Casco Viejo, Panama CityCalle Primera Oeste, San FelipeExplore hotel 
9.502Hotel La Compañía Casco AntiguoAvenida A, Esquina Calle 8Explore hotel 
9.403The Santa Maria, a Luxury Collection Hotel & Golf Resort, Panama CitySanta Maria BoulevardExplore hotel 
9.204Bristol Panama, a Registry Collection HotelAvenida Aquilino de La GuardiaExplore hotel 
9.205Global Hotel PanamaCalle 54 Este y Samuel LewisExplore hotel 
9.206The Westin PanamaLa Rotonda Street, Costa del EsteExplore hotel 
9.007Hotel Las Americas Golden Tower PanamáAv. Balboa con Calle 53Explore hotel 
9.008Hotel San FelipeAve. Central entre calle 8a y 9aExplore hotel 
8.909American Trade HotelPlaza Herrera Casco ViejoExplore hotel 
8.810JW Marriott PanamaCalle Punta Colon, Punta PacificaExplore hotel 
8.811Le Meridien PanamaCalle Uruguay & Balboa AvenueExplore hotel 
8.712Aloft by Marriott PanamaVia Israel & Calle 76Explore hotel 
8.713W PanamaCalle Aquilino de la Guardia & Calle 50Explore hotel 
8.714Waldorf Astoria Panama47th St. & Uruguay StreetExplore hotel 
8.715Waymore Hotel Spa & CasinoAvenida Eusebio A. MoralesExplore hotel 
8.616Central Hotel Panama Casco ViejoPlaza de la Independencia Casco ViejoExplore hotel 
8.617Sortis Hotel, Spa & Casino, Autograph Collection56 y 57 East Street, ObarrioExplore hotel 
8.518Megapolis Hotel PanamaAve. Balboa al lado de MulticentroExplore hotel 
8.519Sheraton Grand PanamaVía Israel y Calle 77 San FranciscoExplore hotel 
8.320Intercontinental Miramar Panama by IHGMiramar Plaza, Balboa AvenueExplore hotel 
8.321Radisson Hotel Panama CanalAmador Avenue & Van Hook StreetExplore hotel 
8.222Decapolis Hotel Panama CityAvenida Balboa Con MulticentroExplore hotel 
7.823Hotel El Panama by Faranda Grand, a member of Radisson IndividualsVia Espana 111Explore hotel - 24Gran Evenia Panamá HotelExplore hotel
- 25Riu Plaza PanamáExplore hotel
Four-star
Four-star favorites
10.001Hyatt Regency Panama CityExplore hotel 
9.802La Concordia Boutique HotelAve Central & Calle A & Calle BExplore hotel 
9.403Ramada Plaza by Wyndham Panama Punta PacificaVia Israel y Calle 71, San FranciscoExplore hotel 
9.304La Concordia Boutique HotelCasco Antiguo, Ciudad de PanamáExplore hotel 
9.005Exe Oriental PanamáAvenida 2da Sur, Obarrio, Bella VistaExplore hotel 
8.906Residence Inn by Marriott Panama CityCALLE RAMON H JURADO EDIFICO PExplore hotel 
8.907The Executive HotelAvenida Aquilino de la Guardia y calle 52Explore hotel 
8.808AC Hotel by Marriott Panama CityCalle Ricardo Arias 14Explore hotel 
8.809Best Western Plus Panama Zen HotelCalle Gaspar Hernandez y Via ArgentinaExplore hotel 
8.810Hilton PanamaBalboa Ave. and Aquilino De La GuardiaExplore hotel 
8.811Hotel Dann Carlton Marinn Place Panama Financial DistrictAvenida Aquilino de la Guardia, betweenExplore hotel 
8.712Hotel PrincipeVia ArgentinaExplore hotel 
8.713Marriott Executive Apartments Panama City, FinisterreCalle Colombia Y Ave.,3ra A Sur, Bella VExplore hotel 
8.714Tryp by Wyndham Panama CentroVia Veneto, El Cangrejo BellavistaExplore hotel 
8.615Hilton Garden Inn Panama City Downtown, PanamaEusebio A Morales y calle 49A oesteExplore hotel 
8.516Courtyard by Marriott Panama Multiplaza MallVia Israel Multiplaza Pacific MallExplore hotel 
8.517Hotel Coral SuitesCalle D El CangrejoExplore hotel 
8.518Riande Urban HotelEl Cangrejo; Calle Eusebio A, MoralesExplore hotel 
8.419Crowne Plaza Panama by IHGAve. Manuel Espinosa BatistaExplore hotel 
8.320Holiday Inn Panama Canal by IHGAve. Omar Torrijos Herrera ClaytonExplore hotel 
8.221Hotel Casa MillerEstacion 5 de Mayo entre Av. PeruExplore hotel 
8.122Summit Rainforest Golf Resort & All InclusiveOmar Torrijos AveExplore hotel - 23Hotel Magnolia BoutiqueExplore hotel
- 24Marriott Panama Hotel - AlbrookExplore hotel
- 25Plaza Paitilla InnExplore hotel
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Hotel info and reviews come from third-party sources.